Publications
From IITK
- Diazepam-based covalent modifiers of GPX4 induce ferroptosis in liver cancer cells
- Dharmendra K. Yadav, Sona Tiwari, Sathyapriya Senthil, Sai Kumari Vechalapu, Santhosh Duraisamy, Viral Rawat, Mohammed Isfahur Rahman, Shweta Khanna, Dharmaraja Allimuthu*. Chem. Comm. (2024, Accepted)
- 2-Amino benzophenone derivatives for targeted ferroptosis induction in cancer cells
- Dharmaraja Allimithu, Dharmendra K. Yadav, Shweta Khanna, Sai Kumari Vechalapu, Sona Tiwari. Indian Patent, 202311063839 (46/2023)
- Mn(II) Polypyridyl Complexes: Precursors to High Valent Mn(V)=O Species and Inhibitors of Cancer Cell Proliferation
- Pragya Arora, Sikha Guota, Sai Kumari Vechalapu, Rakesh Kumar, Ayushi Awasthi, Sathyapriya Senthil, Shweta Khanna, Dharmaraja Allimuthu*, Apparao Draksharapu*. Chem. Eur. J. (2023) (Collaboration with Dr. Apparao Lab)
- Adopting drug repurposing to overcome drug resistance in cancer
- Eswar Shankar*, VIsh Subramaniam*, Dharmaraja Allimuthu*. Front Cell Dev. Biol. (2023, Editorial)
- Facile synthesis of nitroamino-1, 3, 4-oxadiazole with azo linkage: a new family of high-performance and biosafe energetic materials.
- Shreyasi Banik, Pradeep Kumar, Vikas D Ghule, Shweta Khanna, Dharmaraja Allimuthu, Srinivas Dharavath*. J. Mat. Chem A. (2023, a support collaboration role)
- Nitroisobenzofuranone, a small molecule inhibitor of multidrug-resistant Staphylococcus aureus targets peptidoglycan biosynthesis.
- Viral Rawat, Sona Tiwari, Shweta Khanna, Umang Gupta, S. N. C. Sridhar, Dharmendra Yadav, Grace Kaul, Abdul Akhir, Deepanshi Saxena, Saravanan Matheshwaran, Sidharth Chopra, Dharmaraja Allimuthu*. Chem. Comm. (2022)
Before IITK
- Enhancers of Human and Rodent Oligodendrocyte Formation Predominantly Induce Cholesterol Precursor Accumulation.
- Joel L Sax, Samantha N. Hershman, Zita Hubler, Dharmaraja Allimuthu, Matthew S Elitt, Ilya Bederman, Drew J Adams. ACS Chem. Biol. (2022)
- Screening reveals sterol derivatives with pro-differentiation, pro-survival, or potent cytotoxic effects on oligodendrocyte progenitor cells.
- Joel L Sax, Zita Hubler, Dharmaraja Allimuthu, Drew J Adams. ACS Chem. Biol. (2021)
- Modulation of lanosterol synthase drives 24,25-epoxysterol synthesis and oligodendrocyte formation.
- Zita Hubler, Ryan M. Friedrich, Joel L. Soz, Dharmaraja Allimuthu, Farrah Gao, Adrianna M. Rivera-Leon, Matthew J. Pleshinger, Ilya Bederman, Drew J Adams. Cell Chem. Biol. (2021)
- Chemoproteomics of an Indole-Based Quinone Epoxide Identifies Druggable Vulnerabilities in Vancomycin-Resistant Staphylococcus aureus .
- Amogh Kulkarni, Isha Soni, Dhanashree S. Kelkar, Allimuthu T. Dharmaraja, Rathinam K. Sankar, Gaurav Beniwal, Abinaya Rajendran, Sharvari Tamhankar, Sidharth Chopra, Siddhesh S. Kamat, and Harinath Chakrapani. J. Med. Chem (2019)
- Diverse chemical scaffolds enhance oligodendrocyte formation by inhibiting CYP51, TM7SF2, or EBP .
- Dharmaraja Allimuthu#, Zita Hubler#, Fadi J Najm, Hong Tang, Ilya Bederman, William Seibel, Paul J Tesar, Drew J Adams. Cell Chem. Biol. (2019) (# denotes equal authorship)
Zita Hubler#, Dharmaraja Allimuthu#, Ilya Bederman, Matthew S Elitt, Mayur Madhavan, Kevin C Allan, H Elizabeth Shick, Eric Garrison, Molly T Karl, Daniel C Factor, Zachary S Nevin, Joel L Sax, Matthew A Thompson, Yuriy Fedorov, Jing Jin, William K Wilson, Martin Giera, Franz Bracher, Robert H Miller, Paul J Tesar, Drew J Adams. Nature (2018) (# denotes equal authorship)
- 2-Chloropropionamide as a low-reactivity electrophile for irreversible small-molecule probe identification.
- Dharmaraja Allimuthu, Drew J Adams. ACS Chem. Biol. (2017)
- Role of Reactive Oxygen Species (ROS) in Therapeutics and Drug Resistance in Cancer and Bacteria.
- Dharmaraja Allimuthu*. J. Med Chem. (2017)
- Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide.
- Priyanka Tyagi, Allimuthu T Dharmaraja, Ashima Bhaskar, Harinath Chakrapani, Amit Singh. Free Rad. Biol. Med. (2015)
- Substituent effects on reactive oxygen species (ROS) generation by hydroquinones.
- Allimuthu T Dharmaraja, Charu Jain, Harinath Chakrapani. J. Org. Chem. (2014)
- Arylboronate ester based diazeniumdiolates (BORO/NO), a class of hydrogen peroxide inducible nitric oxide (NO) donors.
- Allimuthu T Dharmaraja, Govindan Ravikumar, Harinath Chakrapani. Org. Lett. (2014)
- A small molecule for controlled generation of reactive oxygen species (ROS).
- Allimuthu T Dharmaraja, Harinath Chakrapani. Org. Lett. (2014)
- A phenacrylate scaffold for tunable thiol activation and release.
- Rathinam K Sankar, Rohan S Kumbhare, Allimuthu T Dharmaraja, Harinath Chakrapani. Chem. Commun (2014)
- Synthesis, reactive oxygen species generation and copper-mediated nuclease activity profiles of 2-aryl-3-amino-1, 4-naphthoquinones.
- Vinayak S. Khodade, Allimuthu T Dharmaraja, Harinath Chakrapani. Bioorg. Med. Chem. Lett (2012)
- Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors.
- Allimuthu T Dharmaraja, Mallika Alvala, Dharmarajan Sriram, Perumal Yogeeswari, Harinath Chakrapani. Chem.Commun. (2012)
- Synthesis, thiol-mediated reactive oxygen species generation profiles and anti-proliferative activities of 2, 3-epoxy-1, 4-naphthoquinones.
- Allimuthu T Dharmaraja, Tapan K. Dash, V. Badireenath Konkimalla, Harinath Chakrapani. Med. Chem.Commun. (2012)